Engineering Fundamentals in Life Science

Session 698 - Mathematical Approaches in Systems Biology
This session is devoted to theoretical and computational studies of biological systems. Such systems include protein/DNA interactions, protein/protein interactions, genetic networks, metabolic pathways, and signal transduction pathways. Presentations will focus on theoretical and computational developments for the study of the behavior of these systems in response to stimulation or changes in their kinetic and thermodynamic properties. Contributions of novel computational strategies for systems biology are especially welcome.
Chair: Rajanikanth Vadigepalli
CoChair: Juergen Hahn
  De Novo Protein Design Based on Binding Affinity Predictions for the Discovery of Novel Inhibitors for Complement 3 and HIV-1
Meghan L. Bellows, Ho Ki Fung, Christodoulos A. Floudas
  Quantitative Measurement Technique for Transcription Factor Profiles
Zuyi (Jacky) Huang, Fatih Senocak, Arul Jayaraman, Juergen Hahn
  Reconstructing Transcription Factor Networks Using the Living Cell Array
Eric Yang, Ioannis Androulakis, Martin Yarmush
  Single-Cell Behavior and Population Heterogeneity: An Inverse Modeling Approach for Computing the Intrinsic Physiological State Functions
Konstantinos Spetsieris, Nikos V. Mantzaris, Kyriacos Zygourakis
  Break
  Stochastic Simulation and Systems Analysis of Insulin-Stimulated GLUT4 Translocation
Eric C. Kwei, Kevin R. Sanft, Jason E. Shoemaker, Linda R. Petzold, Francis J. Doyle III
  Small World Network Models of Intercellular Coupling In the Mammalian Circadian Clock
Christina Vasalou, Mark Freeman, Erik D. Herzog, Michael A. Henson
  Microscale Analysis for Quantifying Nitric Oxide Induced Hypoxemia in Methemoglobinemia
Srimoyee Bhattacharya, Saikat Chakraborty

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