Determination of Physiological Modes in Saccharomyces-Cerevisae Culture using Sequential Data Analysis
Abstract
Detecting the physiological mode of microorganism during a culture may allow to better handle behaviour modifications that can affect the productivity. This paper proposes a new sequential method that utilises a classification of directions that generate the subspace orthogonal to the pre-processed measurements. Existence of the orthogonal subspace and the nature of pre-processing are derived from theoretical modelling of the culture. An application to a Saccharomyces Cerevisae culture shows the ability to well isolate main biological phases of the process.