This paper is concerned with the design of Multi-Inputs and Multi-Outputs (MIMO) predictive PID controllers, which have similar features to the model-based predictive controller. A PID type control structure is defined which includes prediction of the outputs and the recalculation of new set points using the future set point data. The optimal values of the MIMO PID gains are calculated using the values of gains calculated from an unconstrained generalised predictive control algorithm. Simulation studies demonstrate the performance of the proposed controller and the results are compared with generalised predictive control solutions.