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**Abstract.**

We address the problem of optimizing operation of a process where
there are extra degrees of freedom, and where the optimum is not at
some constraint. In practice, there are always unknown disturbances
and model uncertainties which make this task complicated. The key idea
of this paper is to turn the non-linear optimization control problem
into a setpoint control problem so that we achieve self-optimizing
control. If this can be done, the task of optimizing operation can be
realized by simple standard control loops, without the need of
solving complex nonlinear optimization problems on-line. The
integrated Petlyuk or dividing-wall distillation column is used as an
example process. The column has two extra degrees of freedom at
steady state, and the challenge is to find a set of feedback
variables, which makes the operation insensitive to disturbances so
that the reported 30% energy savings can be achieved in practice.