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A.C. Christiansen, E.W. Jacobsen, J.D. Perkins and S. Skogestad, ``On the dynamics of batch distillation: A study of parametric sensitivity in ideal binary columns'', AIChE Annual Meeting, Miami Beach, Nov. 1995, Paper 184d.

Abstract.
The paper addresses parametric sensitivity in batch distillation processes. By considering the effect of small changes in the operating parameters, e.g., initial conditions, we show that even ideal binary columns may display highly sensitive regions of operation. Through analysis of a general model we determine operating conditions that favor parametric sensitivity and show that parametric sensitivity in general will be most severe in columns operated with reflux or internal reflux ratio as a manipulated input. The analytical results are verified through numerical computations for several case studies.