Parkinson’s Disease: Modeling the Tremor and Optimizing the Treatment
| Authors: | Haeri Mohammad, Sharif U. of T., Iran (Islamic Republic of)
Sarbaz Yashar, Sharif U. of T., Iran (Islamic Republic of)
Gharibzadeh Shahriar, Amir Kabir U. of T., Iran (Islamic Republic of) |
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| Topic: | 1.1 Modelling, Identification & Signal Processing |
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| Session: | Image Processing and Biomedical Applications |
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| Keywords: | Medical, Optimization, Modelling, Oscillation, Noise characteristics |
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Abstract
Parkinson’s disease is a common neurological disorder, the main symptom of which is tremor. In this study, tremor is modelled using physiological information and clinical recordings. All blocks of the basal ganglia are considered exactly in this model and mathematical relations of each block are designed. Two main therapeutic approaches are implemented on the model. Finally, optimal dose and optimal time of prescribing the drug, Levodopa, is offered. Our results indicate that this model can be used as a primary choice for research on Parkinson’s disease.
