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Preliminary Study of the Heart Rate Variability as a Indicator of the Interaction between the Glycaemia Regulation System and the Autonomous Nervous System

Authors:Viñas Pablo Francisco, Cartif, Spain
Cánepa Lázaro Gorostiaga, Cartif, Spain
Lázaro Enrique Baeyens, Cartif, Spain
Turiel Javier Pérez, Cartif, Spain
González José Ramón Perán, Cartif, Spain
Topic:8.2 Modelling & Control of Biomedical Systems
Session:Control Application to Life Medicine II
Keywords: Biomedical systems, Physiological models, Data acquisition, Feedback systems, Signal processing

Abstract

There have been numerous improvements to optimize the insulin treatment of patients with Diabetes Mellitus during the last years. Several model-based algorithms to regulate the insulin flow from a pump, given a sensor measurement, have been developed. Our opinion is that this kind of algorithms can be improved with information about the state of the autonomous nervous system and in this way we could improve the treatment of these patients. A scheme of glycaemia regulation considering the influence of the Neuro-Endocrine system is proposed here. The results of a preliminary experiment designed to study the relationships between both systems is presented.