Parameter Estimation for a Biological System: Model and Experimentations
Authors: | Lormel Corine, DGA/DCE/CTA, France, Metropolitan Autrique Laurent, DGA/DCE/CTA, France, Metropolitan Serra Jean-Jacques, DGA/DCE/CTA, France, Metropolitan Claudet Bernard, University of Perpignan, France, Metropolitan |
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Topic: | 8.2 Modelling & Control of Biomedical Systems |
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Session: | Parameter Estimation and Kinetic Modelling II |
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Keywords: | Biomedical systems, Mathematical model, Parameter estimation, Optical properties, Thermal diffusivity, Partial differential equation. |
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Abstract
Temperature evolution and skin burn process in biological samples exposed to laser radiation are investigated in this communication. A one-dimensional multi-layered model is presented and transient temperature is numerically estimated using a finite difference method. A damage function corresponding to the extent of burn injury and using the Arrhenius assumptions is proposed. Two experimental benches are presented in order to estimate human skin optical and thermal properties.