15th Triennial World Congress of the International Federation of Automatic Control
  Barcelona, 21–26 July 2002 
MODELING EXERCISE EFFECTS IN TYPE I DIABETIC PATIENTS
Philip J. Lenart and Robert S. Parker
Department of Chemical and Petroleum Engineering
University of Pittsburgh
Pittsburgh, PA 15261
rparker@pitt.edu

A model for glucose metabolism during exercise is developed for use in an automated insulin delivery device. Key changes that occur in the body during exercise are an increase and redistribution of blood flow, increased glucose uptake, and increased glucose production by the liver. A model of glucose and insulin metabolism for exercise intensity less than or equal to 60 percent VOmax2 and duration of less than or equal to 90 minutes has been constructed. The model-generated glucose profiles are consistent with physiological behavior over this time period based on comparisons with literature data.
Keywords: biomedical systems, dynamic modelling, nonlinear models, physiological models, time
Session slot T-Tu-E21: Posters of Agricultural, Biological and Environmental Systems/Area code 4c : Modelling and Control of Biomedical Systems