The enabling methods for advanced interceptors to achieve the hit-to-kill accuracy against targets performing evasive maneuvers including spiraling motion are developed on the basis of one unified theory for the purpose of design and analysis, viz. a contemporary nonlinear robust control theory such as the sliding mode control. The integration of guidance and flight control systems is achieved in a two-loop guidance and flight control system designed in the combined state space of engagement kinematics and vehicle dynamics. The designed guidance-control system performance is verified via computer simulations using a generic endo-atmospheric interceptor model.