Pharmaceuticals |
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| Session 360 - Mixing Issues In the Pharmaceutical Industry | |||
| The utilization of mixing technology in pharmaceutical and biotechnology industries is critical to a broad spectrum of applications. These applications include preparation of APIs, methods of fermentation and cell culture, downstream processing of biologicals, and pharmaceutical operations including suspension handling, and emulsification. Utilization of mixing theory and evolving experimental methods are required for successful development and scale-up. We invite papers in these (and related) areas describing mixing-related process development work, as well as methodologies to scale up or scale down mixing-sensitive processes. | |||
| Chair: | Christopher L. Burcham | ||
| CoChair: | Otute Akiti | ||
| CoSponsor(s): | North American Mixing Forum |
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| 360a | Experimental and Computational Investigation of the Hydrodynamics of Partially Baffled and Unbaffled Stirred Tank Reactor Systems Equipped with a Retreat-Blade Impeller Giuseppe Di Benedetto, Deepak R. Madhrani, Piero M. Armenante |
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| 360b | Low Shear Mixing with a Novel Impeller Design Chris Hibshman, Wojtek Wyczalkowski |
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| 360c | Predictive Modeling for Mixing and Feeding Processes Using Kriging Apporach Zhenya Jia, Eddie Davis, Fernando J. Muzzio, M.G. Ierapetritou |
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| 360d | Enhancement of Shelf-Life and Handling Properties of Drug Nanoparticles: Nanoscale Mixing of Itraconazole with Silica Ganesh Sanganwar, Ram B. Gupta |
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| Break |
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| 360e | A Hydrodynamic Method for the Production of Nanoparticles Eric Jayjock, Fernando J. Muzzio |
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| 360f | Coupled Effects Between Process and Formulation Variables on Rheological Properties of Highly Concentrated Water-In-Oil Emulsions Oscar A. Alvarez, Lionel Choplin, Veronique Sadtler, Marie José Stébé, Philippe Marchal |
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| 360g | Study of Tablet Coating Thickness Uniformity Using Libs, Dem and Compartment Modeling Atul Dubey, Patricia M. Portillo, Fernando J. Muzzio |
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