Pharmaceuticals |
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| Session 480 - Innovations in Biopharmaceutical Process Development | |||
| We seek papers addressing advancement, innovation and application of state of the art bioprocessing solutions to the challenges of development and manufacture of biopharmaceuticals. Papers offering insights on advances in process development, process development tools, processing and monitoring technology, and plant design and management will be included in this session. Also of interest are PAT applications to bioreactors. Novel sensor technologies, intelligent sensors, optimization tools, or multivariate analysis implemented/under development for applications in biopharmaceuticals and pharmaceutical manufacturing, process development or pilot plants are encouraged to apply. | |||
| Chair: | Gregory Frank | ||
| CoChair: | Ashraf Amanullah | ||
| 480a | Liver Tissue Engineering with Inverted Colloidal Crystal Scaffolds for In Vitro Drug Testing Application Jungwoo Lee, Nicholas A. Kotov |
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| 480b | Optimization of ChEmically-Defined Media for High Cell Density Growth of Lactococcus Lactis Using Highly-Efficient Nonlinear Experimental Design Methods Guiying Zhang, David E. Block |
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| 480c | Mixing Studies with Elephant Ear Impellers: Are They Low Shear Agitators? Alvin W. Nienow, Sophie Zhu, Waldek Bujalski, Mark J. H. Simmons |
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| 480d | Evaluation of a Pendulum Agitator In Biopharmaceutical Applications Lauren Speciner, Al Stern, Tom Bewley, Liza Munda, Brad Wolk, Adeyma Arroyo |
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| 480e | Automated Monitoring of Mammalian Cell Cultures Via An Auto-Sampler and An Integrated Multi-Functional off-Line Analyzer Gayle E. Derfus, Daniel Abramzon, Meg Tung, Robert Kiss, Ashraf Amanullah |
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| 480f | The Design and Synthesis of Novel Excipients for the Suppression of Protein Aggregation Curtiss P. Schneider, Bernhardt L. Trout |
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| 480g | Development of a ‘Cycle to Cycle' Control for the Mcsgp-Process for a Monoclonal Antibody Variant Separation Cristian Grossmann, Manfred Morari, Massimo Morbidelli, Guido Ströhlein |
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| Break |
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