Engineering Fundamentals in Life Science | |||
| Session 543 - Drug Delivery (I) | |||
| This session highlights recent research efforts in the broad area of design, characterization (in vitro and in vivo), and development of drug delivery systems with multi-functional properties for targeted and sustained drug delivery. Topics of interest include, but are not limited to: Effects of chemical structure and/or physical properties of drug delivery systems on loading efficiency and release kinetics; functionalizing drug carriers with moieties for specific targeting; blood circulation time and biodistribution of drug-carrier complexes after systemic injection; in vitro and in vivo studies of cellular uptake. | |||
| Chair: | Efrosini Kokkoli | ||
| CoChair: | Stavroula Sofou | ||
| 543a | Design of Targeted Nanocarriers for Optimal Drug Delivery to Stressed Endothelium: a Multiscale Modeling Approach Joshua Weinstein, Neeraj Agarwal, Ravi Radhakrishnan | ||
| 543b | Comparative Analysis of the Uptake and Intracellular Fate of Nanoparticles in Different Epithelial Cell Types Malgorzata S. Cartiera, K. M. Johnson, V. Rajendran, M. J. Caplan, W. Mark Saltzman | ||
| 543c | Efficient Sirna Delivery with Acetylated Polyethylenimine Lily Wong, Daniel W. Pack | ||
| 543d | Biodegradable Spray Dried Microspheres and Discs Delivering Paclitaxel and Etanidazole for the Treatment of Giloma: an in Vivo Subcutaneous Study Benjamin Y. S. Ong, Pavan Kumar Naraharisetti, Jingwei Xie, Chi-Hwa Wang, Nick Sahinidis | ||
| Break | |||
| 543e | Coated Microneedles for Transdermal Drug Delivery Harvinder S. Gill, Mark R. Prausnitz | ||
| 543f | A Biodegradable Fiber for Controlled Delivery of Therapeutics to the Eye Brendan C. Mack, Kenneth W. Wright, Mark E. Davis | ||
| 543g | Drug Elimination Kinetics in the Eye after Subconjunctival Delivery Stephanie H. Kim, Robert J. Lutz, Karl G. Csaky, Craig J. Galban, Nam Sun Wang | ||
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